Cord Blood Stem Cells Information

Dedifferentiation of adult cells into Embryonic stem cell?

To be honest my professor is Korean researcher in US has created the differentiate an adult cell into Embryonic stem cell, using mouse. He did it but, it seems that another researcher stolen or did smth wrong, anyway what ever it was, finally the creator became not him but that person. So I think he wants us to find negative sides of this work (differentiation of adult cells into Ebryonic cell). So please give me more exact negative fact for that. Hope this additiona information wil help you.

Public Comments

1. I'll be honest, this stuff is way beyond my abilities, so I won't pretend that I know what I'm talking about. However, from my brief searches on journal databases it appears that one negative fact about dedifferentiation and the chemical reversine is that it may be a conduit for the formation of cancer. Some scientists believe that it may be possible that the use of reversine for therapeutic purposes may have a negative effect, in that cancer may form from these dedifferentiated cells. Some theories of cancer actually suggest that adult cells have dedifferentiated into stem cells capable of proliferating quickly and without constraint. Here are a couple articles I found: http://www.scripps.edu/chem/ding/Nature.PDF http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=7516873 http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/Cancer.html Thanks for the additional information and I hope I have been able to give you a couple of ideas in your search for some possible negative sides to this new discovery of dedifferentiation of adult cells into embryonic stem cells. This works sounds very interesting and promising, good luck to you and your professor in your research.